The Working Group for Cardiovascular Dynamics and Artifical Organs deals with research, development and clinical application of circulatory assist devices, cardiovascular implants and circulation monitoring and modelling
Our group has half a century (sic!) of tradition in research, and clinical application of Cardiac Assist Devices and Artificial Hearts. In close cooperation with clinicians and biomedical researchers in the Ludwig-Boltzmann-Institute of Cardiovascular Research our group develops components and algorithms for these challenging tasks and support the clinicians in the clinical use. Further topics include vascular prostheses, refinement of diagnostic methods and modelling in silico, in vitro, and in bioreactors. The group cooperates with a large number of international academic and industrial partners. Members of the group have been presidents of International scientific societies working in the field, such as ESAO, ISMCS and ICCAC.
Research Area
- Cardiovascular Simulations and Fluid Dynamics
- Clinical Support and Clinical Research for Assist Devices
- Development of Blood Pumps & Components
- Electrospinning for Grafts and Scaffolds
- In-vitro, Ex-vivo, In-vivo experiments
- Mechanical Characterization of Biomaterials and Soft Tissues
- Monitoring and Control of Cardiac Assist Devices
- Neural Control of the Cardiac Activity
Principal Investigator
Francesco Moscato
P +43 (0)1 40400-39830
Deputy Principal Investigator
Thomas Schlöglhofer
P +43 (0)1 40400-27280 or -20010
Members
Theodor Abart
Hebe Al Asadi
Philipp Aigner
Laurenz Berger
Marta Bonora
Lorenzo Civilla
Christian Grasl
Max Haberbusch
Benedikt Riebartsch
Johanna Schachl
Martin Stoiber
Ingo Weigel
Gregor Widhalm
- Adrian Aistleitner
- Alexander Akhgar
- Matthias Arras
- Michael Baumann
- Philipp Cichra
- Michael Desch
- Daniel Fechtig
- Katharina Frieberger
- Silvia Frullini
- Mojgan Ghodrati
- Joanna Grabska
- Anna-Sophie Grausenburger
- Christoph Gross
- Zeno Hartner
- Veronika Hörmann
- Thayanya Khienwad
- Markus Königshofer
- Bettina Kronsteiner
- Christian Lueder
- Angelika Marschütz
- Alexander Maurer
- Martin Maw
- Peter Michailovics
- Marcel Migas
- Phornphop Nayanatr
- Alexander Neumayer
- Alexander Nikodijevic
- Sophie Nilsson-Zcagicek
- Henrik Ober
- Lotte Olberts
- Lea Plunger
- Nikolaos Politis
- Stefan Riegler
- Heinrich Schima (ehemaliger Gruppenleiter)
- Shabo Sontansai
- Katharina Tischler
- Peter Voitl
- Michael Vollkron
- Walter Wallner
- Albert Werner
- Florian Wimmer
- Christian Wirrmann
- Feride Yavuz
- Eva Zach
- Lydia Zapusek
- Markus Ziegltrum
- Development of Cardiac Assist Devices, their components and clinical application (Ludwig Boltzmann-Institute of Cardiovascular Research)
- Development of vascular Grafts (Ludwig-Boltzmann-Institute of Cardiovascular Research)
- NeuHeart – Horizon 2020 EU-Project (2019)
- TEX-hype - Austrian Research Promotion Agency FFG Project (2021)
Book about the history of Artificial-Heart Research in Vienna
G. Dorffner, W.M.Wallner; H. Schima(Hrsg), mit Bildern von B. Croy und Riedler: Kein Puls und doch am Leben! – 50 Jahre Kunstherzforschung und –Therapie in Wien (314 S, LBG Eigenverlag Wien)
Selected peer-reviewed publications
- Schima H, Vollkron M et al.: First clinical experience with an automatic control system for rotary blood pumps during ergometry and right-heart catheterization. J Heart Lung Transplant. 2006 Feb;25(2):167-73.
- Schima H, Schlöglhofer T et al.: Usability of ventricular assist devices in daily experience: a multicenter study. Artif Organs. 2014 Sep;38(9):751-60.
- Schlöglhofer T, Horvat J et al.: A Standardized Telephone Intervention Algorithm Improves the Survival of Ventricular Assist Device Outpatients. Artif Organs. 2018 Oct;42(10):961-969.
- Zimpfer D, Aigner P et al.: Evaluation of the HeartWare ventricular assist device Lavare cycle in a particle image velocimetry model and in clinical practice. Eur J Cardiothorac Surg. 2016 Nov;50(5):839-848.
- Gross C, Moscato F et al.: Hemodynamic exercise responses with a continuous-flow left ventricular assist device: Comparison of patients' response and cardiorespiratory simulations. PLoS One. 2020 Mar 18;15(3):e0229688.
- M. Haberbusch: Development of phenomenological models and control strategies to restore vagal heart rate control through closed-loop vagus nerve stimulation; Doctoral Thesis, Medical University of Vienna 2023
- M. Maw: Development and Evaluation of a Sensorless Modular Physiological Control System for Left Ventricular Assist Devices; Doctoral Thesis, Medical University of Vienna 2022
- C. Grasl: Improvement of electrospinning methods for the production of small diameter vascular grafts; Doctoral Thesis, Medical University of Vienna 2022
- P. Aigner: Studies on the fluid mechanical causes of thrombus formation during the use of mechanical cardiac assist devices; Doctoral Thesis, Medical University of Vienna 2022
- M. Ghodrati: Numerical simulation of intra-cardiac flow fields under mechanical circulatory support: consideration of different numerical algorithms and ventricular geometries; Doctoral Thesis, Medical University of Vienna 2021
- M.H. Stoiber: Mechanical characterization of small blood vessels and vascular grafts; Doctoral Thesis, Medical University of Vienna 2021
- Thananya Khienwad: Investigation of cardiac flow patterns in patients with cardiac assist devices using Particle Image Velocimetry: Effects of speed changes and particular patient-specific cardiac geometries; Doctoral Thesis, Medical University of Vienna 2021
- C. Gross: Non-invasive diagnostic tools to optimize therapy in patients with implantable left ventricular assist devices, Doctoral Thesis, Medical University of Vienna 2020
- M. Granegger: Interaction between the heart and a rotary pump: Simulation and ex-vivo evaluation; Medical University of Vienna 2013
- P. Naiyanetr: Continuous Assessment of cardiac contractility during rotary blood pump support, Medical University of Vienna 2010
- P. Voitl: Physiologic effects of rotary blood pumps; Medical University of Vienna 2008
- F. Moscato: Investigating the interaction betwen the cardiovascular system and an axial flow VAD; University of Calabria 2007