Competence Team Implanted Devices

• Implant Technology 
• Functional Electrical Stimulation 
• Engineering in Medicine 
• Vienna Int. Workshop on FES

• Research Neural Interfaces Multicontact Electrode for preclinical trials to verify the long-term stability of the multicontact electrode (2024).
  Use of MiniVstim implants in a research collaboration (MedEl) §27 Contract research
• Verification of an automated cadence control for FES cycling (2023):
  Non-interventional study according to MPG in healthy volunteers, to analyse the accuracy of a cadence control for cycling with functional electrical stimulation (EC number: 2010/2022)

• Performance improvement in FES cycling in subjects with paraplegia through improved stimulation techniques and active breathing - a pilot study (2023-2028):
  Non-interventional study according to MPG with the aim to increase performance during cycling with functional electrical stimulation, in patients with complete paraplegia. Within the framework of this project, one patient is also to be prepared for participation in the Cybathlon 2024 (EC number: 1673/2023).

• Reverse end-to-side neurorrhaphy: axonal and terminal distribution (2023- 2024):
  Internal research collaboration with the Clinical Laboratory for Bionic Limb Reconstruction for the electrophysiological study of the functional changes of an "end-to-side" nerve transfer in the upper limb. §27 Contract research

• Evaluation of different conduits for reconstruction of critical nerve defects (2023):
  Internal scientific collaboration with the Division of Plastic and Reconstructive Surgery from the Medical University Vienna §26 contract research

• Evaluation of fresh versus predegenerated nerve grafts in reconstruction of critical nerve defects (2023):
  Internal scientific collaboration with the Clinical Laboratory for Bionic Limb Reconstruction from the Medical University Vienna §27 contract research
• Electroneurographic assessment of a resurfaced glabourous skin transplant (2023):
  Internal scientific collaboration with the Clinical Laboratory for Bionic Limb Reconstruction from the Medical University Vienna §27 contract research
• Influence of "Personal Stress Level" on Sicca Syndrom (2023):
  Internal scientific collaboration with the Department of Physical Medicine from the Medical University Vienna. §27 contract research
• Advanced Biofeedback Hardware and evaluation Software (2023-2025):
  Scientific collaboration with company Insight Instruments, §27 contract research
• Peripheral Nerve Pacing to Restore Blink in a Large Animal Model of Facial Paralysis (2021-22):
  Scientific collaboration with Mayo Clinic MN USA, §27 contract research
• Evaluation of a Current Rooting System for FES (2020-2021):
  Interne Forschungskooperation zur Ermittlung von Selektivität und Effektivität eines implantierbarem Systems mit gezielter Führung des Stimulationsstroms. §27 Auftragsforschung
• Electroneurographic assessment of a glabourous skin transplant (2021):
  Interne Forschungskooperation zur elektrophysiologischen Untersuchung der sensorischen Nervensignale eines Hauttransplantats auf verschiedene Stimuli. §27 Auftragsforschung
• Development and application of implantable pulse generator for neuromuscular activation in mice (2019-2020):
  Scientific collaboration with Liverpool John Moores University, §27 contract research
• Chronic electrical stimulation for the therapy of the aged voice (2019-2022)
  Scientific collaboration with Medical University Graz, §27 contract research
• Motoric endplate reinnervation and axonal regeneration using experimental adipose stem cell transplantation (2019-2021)
  Internal scientific collaboration with the Division of Plastic and Reconstructive Surgery
• TrackWear: Trackside Working Wearables holding Warning Actuators (2019)
  FFG 855012, in cooperation with Rail Expert Consult GmbH and Spath Micro Electronic Design GmbH
• Messung und Auswertung physiologischer Parameter (Biofeedback) (since 2004)
  long term cooperation with Insight Instruments, FFG and §27 contract research
• Stress evaluation of surgeons and patients during cataract surgeries (2018)
  in cooperation with the Vienna Institute for Research in Ocular Surgery (VIROS) and Department of Ophthalmology at the Vienna Hanusch Hospital
• Invasive Mensch-Maschine-Schnittstellen/INOPRO (2019)
  Interne Forschungskooperation mit dem klinischen Labor für Bionische Extremitätenrekonstruktion
• Theranostische Implantate zur Elektrodentestung (2018)
  Forschungskooperation mit dem Christian Doppler Labor für Wiederherstellung von Extremitätenfunktionen Medizinische Universität Wien, Otto Bock Healthcare Products GmbH, IBMT Fraunhofer-Institut für Biomedizinische Technik, St. Ingbert, §27 Auftragsforschung

Selected peer-reviewed publications

• Tereshenko V, Dotzauer DC, Schmoll M, Harnoncourt L, Carrero Rojas G, Gfrerer L, Eberlin KR, Austen WG, Blumer R, Farina D, Aszmann OC. Peripheral neural interfaces: Skeletal muscles are hyper-reinnervated according to the axonal capacity of the surgically rewired nerves. Science Advances 10: eadj3872, 2024.

• Kirsch A, Gerstenberger C, Jakubaß B, Tschernitz M, Perkins JD, Groselj-Strele A, Lanmüller H, Kniesburger S, Döllinger M, Gugatschka M. Bilateral Functional Electrical Stimulation for the Treatment of Presbyphonia in a Sheep Model. The Laryngoscope. 2023 Aug 19;

• Ostermeier M, Schmoll M. Exploring methods for targeted activation of the sympathetic nervous system without exercise: Finding solutions to enhance FES-cycling performance for individuals with SCI. Current Directions in Biomedical Engineering 8: 21–24, 2022.

• Schmoll M, Le Guillou R, Fattal C, Coste CA. OIDA: An optimal interval detection algorithm for automatized determination of stimulation patterns for FES-Cycling in individuals with SCI. Journal of NeuroEngineering and Rehabilitation 19: 39, 2022.

• Cap V, Palkovits S, Bijak M, Ruiss M, Schmoll M, Findl O. New approach to quantifying acute stress in cataract surgeons to investigate the relationship between surgeon experience and intraoperative stress. J Cataract Refract Surg. 2022 May 1;48(5):549-554.

• Viggars MR, Sutherland H, Lanmüller H, Schmoll M, Bijak M, Jarvis JC, Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training. FASEB J. 2023 Jan;37(1):e22686. doi: 10.1096/fj.202201418R.

• Schmoll, M. et al., Standardizing fatigue-resistance testing during electrical stimulation of paralysed human quadriceps muscles, a practical approach. J Neuroeng Rehabil. 2021 Jan 21;18(1):11

• Guillou, R, et al., A Novel Framework for Quantifying Accuracy and Precision of Event Detection Algorithms in FES-Cycling. Sensors (Basel). 2021 Jul 3;21(13):4571

• Bijak,M, et al., MiniVStimA: A miniaturized easy to use implantable electrical stimulator for small laboratory animals. PLoS One. 2020 Oct 30;15(10):e0241638.

• Naeem, J., (2020). Electrical stimulator with mechanomyography-based real-time monitoring, muscle fatigue detection, and safety shut-off: a pilot study, Biomedical Engineering / Biomedizinische Technik (published online ahead of print), 20190191.
• Taylor, M. et al., (2020). Lessons from Vienna: stakeholder perceptions of functional electrical stimulation technology and a conceptual model for practice. Disability and Rehabilitation: Assistive Technology, 15(1), 37–44.
• Naeem, J., (2019). Mechanomyography-based muscle fatigue detection during electrically elicited cycling in patients with spinal cord injury. Medical and Biological Engineering and Computing, 57(6).
• Schmoll, M. et al., 2018. SpillOver stimulation: A novel hypertrophy model using co-contraction of the plantar-flexors to load the tibial anterior muscle in rats. PLoS One, 13(11):e0207886.
• Schmoll, M, et al. 2017. A novel miniature in-line load-cell to measure in-situ tensile forces in the tibialis anterior tendon of rats. PLoS One, 12(9):e0185209.
• Schmoll, M. et al. 2017. In-situ measurements of tensile forces in the tibialis anterior tendon of the rat in concentric, isometric, and resisted co-contractions. Physiol Rep. 5(8). pii: e13245.
• Taylor M. et al., (2017). The Vienna FES Interview Protocol – A mixed-methods protocol to elucidate the opinions of various individuals responsible for the provision of FES exercise, Eur J Transl Myol. 2017 Jun 27; 27(3): 6604.
• Coste C. et al., (2016).FES in Europe and Beyond: Current Translational Research Eur J Transl Myol. 2016 Dec 15; 26(4): 6369.
• Derntl B. et al., (2015).Stress matters! Psychophysiological and emotional loadings of pregnant women undergoing fetal magnetic resonance imaging BMC Pregnancy Childbirth. 2015; 15: 25.
   

• Marie Ostermeier, “Exploring strategies for targeted activation of the sympathetic nervous system without exercise", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2022)
• Emil Ogrodnik, " Method for the evaluation of the performance of a multi-channel nerve cuff electrode coupled with a transcutaneous transfer array", Master Thesis, (Technical University of Vienna, 2022)
• Yihau Zheng, "Impact of music intervention on anxiety stress level of a planned professional dental hygiene – data collection and evaluation", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2022)
• Pia Hisberger, "Comparing three stress evaluation methods as a part of cataract operations", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2021)
• Fred Bucek, " Comparison of Skin Impedance Responsivity on Different Body Locations: Hardware, Software, and Measurements", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2020)
• Paschon Karin, “Value of surface electrography as a troubleshooting tool in deep brain stimulation: potential in clinical use” Master Thesis (Medical University of Vienna, Vienna, Austria 2019
• Sebastian Brettlecker, " Evaluation and classification of skin conductance profiles", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2019)
• Dominik David, "Multi-site measurement of skin conductance and skin capacitance using alternating current" , Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2019)
• Orissa Deubner, " Bilateral Cataract Surgery Patients: Evaluation of Emotional Arousal using Skin Conductance", Master Thesis, (University of Applied Sciences Technikum Wien, 2019)
• Veronika Cap, "Measuring Skin Conductance and other Physiologic Parameters to Monitor Psychological Stress", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2018)
• Schmoll Martin, “Development of a basic research model for muscular hypertrophy by means of implantable pulse generators” Doctoral Thesis PhD (Medical University of Vienna, Vienna, Austria 2017)
• Florian Starzengruber, "Evaluating the physiological "stress level" of patients before and during cataract surgery", Master Thesis, (University of Applied Sciences Technikum Wien, 2017)
• Lukas Proksch, " MiniVstim Testing Tool - test automation of miniaturized, implantable stimulators", Bachelor Thesis, (University of Applied Sciences Technikum Wien, 2016)
• Sommer Christoph, “Development of a 45W Transcutaneous Energy Transmission System for a Pulsatile Total Artificial Heart” Doctoral Thesis PhD (Medical University of Vienna, Vienna, Austria 2016)